Psychopharmacological Potentials of Methanol Leaf Extract of Securinega virosa Roxb (Ex Willd) Baill. in Mice

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Isolation of bergenin from the root bark of Securinega virosa and evaluation of its potential sleep promoting effect

Objectives: Securinega virosa Roxb (Ex Willd) Baill (Euphorbaiceae) root bark has been reportedly used in African traditional medicine in the management of mental illnesses. Previously, the sleep-inducing potential of the crude methanol root bark of Securinega virosa extract and its butanol fraction have been reported. The study aimed to isolate and characterize the bioactive constituent that m...

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Isolation of bergenin from the root bark of Securinega virosa and evaluation of its potential sleep promoting effect.

OBJECTIVES Securinega virosa Roxb (Ex Willd) Baill (Euphorbaiceae) root bark has been reportedly used in African traditional medicine in the management of mental illnesses. Previously, the sleep-inducing potential of the crude methanol root bark of Securinega virosa extract and its butanol fraction have been reported. The study aimed to isolate and characterize the bioactive constituent that ma...

متن کامل

isolation of bergenin from the root bark of securinega virosa and evaluation of its potential sleep promoting effect

objectives: securinega virosa roxb (ex willd) baill (euphorbaiceae) root bark has been reportedly used in african traditional medicine in the management of mental illnesses. previously, the sleep-inducing potential of the crude methanol root bark of securinega virosa extract and its butanol fraction have been reported. the study aimed to isolate and characterize the bioactive constituent that m...

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Behavioural effects of the methanolic root bark extract of Securinega virosa in rodents.

Securinega virosa is used traditionally as sedative in children and in mental illnesses. In this study, the behavioral effects of methanolic root bark extract of S. virosa were investigated in mice. The results revealed that the extract significantly (P<0.05) and dose-dependently reduced the onset and prolonged the duration of sleep. The extract significantly (P<0.05) decreased exploratory acti...

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CNS Depressant and Antinociceptive Effects of Different Fractions of Pandanus Foetidus Roxb. Leaf Extract in Mice.

BACKGROUND Various parts of Pandanus foetidus Roxb. are used as traditional medicines. However, scientific reports concerning the effect of this plant on central nervous system (CNS) depression and analgesia are unavailable. This study investigated the CNS depressant and antinociceptive effects of Pandanus foetidus leaf extracts in a rodent model. METHODS The sedative and anxiolytic activitie...

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ژورنال

عنوان ژورنال: Pakistan Journal of Biological Sciences

سال: 2014

ISSN: 1028-8880

DOI: 10.3923/pjbs.2014.855.859